- 产品名称:37450动态足底触觉仪
- 订货号:tlyon000402
- 品牌名称:意大利Ugo
37450 - 动态足底触觉仪
动态足底触觉仪是用以自动评估啮齿类动物跖面的“触觉感应”。它与电子触觉测量(Electronic Von Frey )和足底触觉测量(Plantar Von Frey )类似,不同之处在于它能记录持续时间和爪缩回时的作用力。
可移动的触觉刺激装置放于实验动物足底,可根据实验人员需要设定力的大小和力增大的速度等。
触觉测量套件( Von Frey )以每次增加直径0.05mm的细丝增加施力,直到受试动物的爪抽搐。
动态足底触觉计的新模式为:
一台可移动的触觉刺激装置,配备刺激丝和可调整角度的镜子;
实为一微电子处理单位,提供数字显示、内部数据存储、可用闪存导出数据、可外接打印机;
宽敞的实验操作平台;
模块化的动物笼,可自由组合3-12个隔间。
特征
优点
仪器自动施力
施力速度、方向等保持一致性
操作人员只需按动开关
相比用Von Frey测试,本实验时间短,且操作人员不会感到沉闷
力的大小和增加量可预置
更多参数符合实验需要
规格:
开始:
软键
可设力范围:
0 - 50.0 g, 分辨率为0.5 g
可设力增加率:
1 - 50 s, 分辨率为1s
着力丝移动范围;
12 mm
实验时间:
液晶屏显示,分辨率为0.1s
连接电脑:
DELTA 9-pin 连接线
电源:
规格:
动物罩子:
85-264 VAC - 50-60Hz - 20 W max
85 x 40 x 40 cm
3个,每个20x20x14(h) cm
净重:
12.50 Kg.
毛重:
包装规格:
约21.50 Kg
98x49x47cm
附件:
37000-145:
面板内嵌式热敏打印机
57145:
37450-278
37100
微型热敏打印机
外加刺激,穿孔平台和动物保护罩
两组Durham动物抓持器,针对面部疼痛实验
参考文献:
提及动态足底触觉仪的文献:
- R. Lu, A. Schmidtko: “Direct Intrathecal Drug Delivery in Mice for Detecting In Vivo Effects of cGMP on Pain Processing” Methods in Molecular Biology 1020: 215-221, 2013
- I.Q. Russe et alia: “Activation of the AMP-Activated Protein Kinase Reduces Inflammatory Nociception” Journal of Pain 2, 2013
- J. Btesh et alia: “Mapping the Binding Site of TRPV1 on AKAP79: Implications for Inflammatory Hyperalgesia” J. Neuroscience 33 (21): 9184-9193, 2013
- V. Brázda et alia: “Dynamic Response to Peripheral Nerve Injury Detected by In Situ Hybridization of IL-6 and its Receptor mRNAs in the Dorsal Root Ganglia is not Strictly Correlated With Signs of Neuropathic Pain” Molecular Pain 9(42), 2013
- V. Shunmugavel et alia: “Simvastatin Ameliorates Cauda Equina Compression Injury in a Rat Model of Lumbar Spinal Stenosis” J. Neuroimmune Pharmacology 8 (1): 274-286, 2013
- O. Coste et alia: “The p21-activated kinase PAK 5 is involved in formalin-induced nociception through regulation of MAP-kinase signaling and formalin-specific receptors” Behavioural Brain Research 234 (1): 121-128, 2012
- M.K. Boettger et alia: “Differential Effects of Locally and Systemically Administered Soluble Glycoprotein 130 on Pain and Inflammation in Experimental Arthritis” Arthritis Research & Therapy 12 (R140): 1-9, 2010
- A.L.M. Scott and M.S. Ramer: ” Schwann Cell p75NTR Prevents Spontaneous Sensory Reinnervation of the Adult Spinal Cord” Brain: 1-12, 2010
- M. Rosemann et alia: “Microphthalmia, Parkinsonism, and Enhanced Nociception in Pitx3416insG Mice” Mamm Genome 21: 12-27, 2010- D. Piomelli et alia:” Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism”.Nature NSC, 2010
- L. Ramer et alia: "Rho-Kinase Inhibition Enhances Axonal plasticity and Attenuates Cold Hyperalgesia after Dorsal Rhizotomy" J. Neuroscience, 24 (48), 10796-10805, 2004
- E. Escribano et alia: "Rapid Human Skin Permeation and Topical Anaesthetic Activity of a New Amethocaine Microemulsion" Skin Pharmacol. Physiol., 18, 294-300, 2004
- G. Villetti et alia: "Antinociceptive Activity of the N-Methyl-D-aspartate Receptor Antagonist N-(2-Indanyl)-glycinamide Hydrochloride (CHF3381) in Experimental Models of Inflammatory and Neuropathic Pain" J. Pharmacol. Exper. Therap., 306, 804-814, 2003- M. Isabel Arévalo et alia: "Thermal Hyperalgesia and Light Touch Allodynia After Intradermal Mycobacterium butyricum Administration in Rat" Inflammation, 27 (5), 293-299, 2003Durham Holders for Orofacial Stimulation- F.G. Garrett, P.L. Durham et alia: “Validation of a Novel Rat-Holding Device for studying heat- and mechanical-Evoked Trigeminal Nocifensive Behavioral Responses” J. Orofacial Pain, 26 (4): 336- 344,2012- F.G. Garrett, P.L. Durham et alia: “Development of a novel device for measuring withdrawal latency by thermal stimulation in rodent facial pain models using the Hargreaves Plantar Apparatus” Poster presented at SFN 2010*本产品非医疗器械,不能用于临床诊断和治疗,仅科研用途!*
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